NFL Picks sets up the winless St. Louis Rams taking on the unbeaten Green Bay Packers in NFL action on Sunday at Lambeau Field (1 pm ET, FOX).

The Packers opened as 10.5-point favorites but have been quickly bet up to 15-point favorites in NFL Odds at most sportsbooks. Moneyline odd have Green bay as a -1000 favorite and St. Louis as a +700 underdog. The over/under total is at 47.5 after opening at 48.

Sports Picks fans know that St. Louis is 0-4 straight up and against the point spread. The Rams are coming off a bye week and in their last game on Oct. 2 lost 17-10 against the Washington Redskins. They failed to cover as a 3-point home underdog and the score was under the total of 44.5.

Aaron Rodgers and the Packers are a perfect 5-0 SU and a near-perfect 4-1 ATS. Green Bay won 25-14 against the Atlanta Falcons on Sunday Night Football. The Packers covered as a 6-point road and the score was under the total of 54.

NFL Betting fans should note St. Louis is 0-5 SU and ATS in its last five games overall, and 3-19 SU in its last 22 games on the road. Green Bay is 5-0 SU in its last five games, both overall and at home. The total has gone over in four of Green Bay’s last six games overall, and in seven of Green Bay’s last eight games at home.

Head-to-head, Green Bay has a slight edge straight up at 5-4 in the past nine meetings but St. Louis has the edge against the number at 5-4 ATS. The teams last met Sept. 27, 2009, when the Packers won 36-17 and cashed as a 6.5-point road favorite.

NFL Picks sets up an NFC South division battle on Sunday when the New Orleans Saints and the Carolina Panthers square off at Bank of America Stadium.

This divisional clash starts at 1 pm ET and can be seen on regional FOX stations.

NFL Betting had the Saints opening as 7-point road favorites but they have been bet down slightly to -6.5, and -6 at some books. The moneyline has New Orleans a -300 favorite after opening at -260, and Carolina a +250 underdog after opening at +230. The over/under total is at 52.5 after opening at 53.  

New Orleans is 3-1 SU, winning three straight since dropping the NFL season opener against the defending Super Bowl champion Green Bay Packers. The Saints have also covered the spread in three of their four games. Last Sunday, New Orleans beat the Jacksonville Jaguars 23-10 and cashed as a 9-point road favorite. The score was under the total of 44.5.

Carolina is 1-3 SU but has been good to point spread bettors with a 3-1 record against the spread. The Panthers lost 34-29 against the Chicago Bears in the Windy City last Sunday but covered as a 7-point road underdog. The score went over the total of 41.

Head-to-head, Carolina has got the better of the Saints at 6-4 straight up and 7-3 against the spread in the past 10 meetings. But the Saints won both meetings last season: 34-2 as a 6-point road favorite on Nov. 7, and 16-14 as a 12.5-point home favorite on Oct. 3.

NFL Football Tips previews the Detroit Lions and the Dallas Cowboys clashing in Week 4 National Football League action on Sunday at Cowboys Stadium (1 pm ET, FOX).

The Lions’ success so far this season has driven the point spread from its opening of -3 in favor of Dallas to a pick’em at most sportsbooks. The Cowboys are a -125 moneyline favorite and the Lions a slight +105 underdog, but those numbers will likely change by game time, as well.

The over/under has dropped slightly from the opening of 47 down to 46.5.

About 69 per cent of the bets placed on this game so far are on the Lions to cover the spread.

Detroit (3-0 SU, 2-0-1 ATS) beat NFC North division rival Minnesota Vikings 26-23 on Sunday. That score was a push as the Lions were 3-point road favorites. The score went over the total of 44.5.

Dallas (2-1 SU, 1-1-1 ATS) beat the Washington Redskins 18-16 in its home opener on Monday Night Football. But the Cowboys could not cash as 3.5-point home favorites. The score stayed under the total of 45.

The Lions have been a cover machine for NFL Betting fans, as they are 7-0-1 ATS in their last eight overall. They are also undefeated in their past five going back to last season. Detroit is 4-1 SU in its last five on the road.

The Cowboys are 4-2 SU and 1-4-1 ATS in their last six overall and 3-6 SU and ATS in their last nine games at home.

Head-to-head, Dallas is 5-3 SU and ATS in the past meetings, including a 35-19 victory on Nov. 21 last season. The covered as a 5.5-point home favorite.

Football Picks sets up the Dallas Cowboys looking for their first win of the NFL season when they face the San Francisco 49ers on Sunday at Candlestick Park (4:05 pm ET, FOX).

NFL Odds opened with the Cowboys as 3-point favorites and they have held steady at that number, with a couple of sportsbooks having them at -2.5. Dallas opened as a -150 moneyline favorite and has been bet down to -170, and the 49ers are a +145 underdog. The over/under is at 42.5 after opening at 41.5.

Dallas (0-1 SU, 1-0 ATS) blew a fourth-quarter lead and lost 27-24 to the New York Jets on Sunday Night Football last Sunday. But the Cowboys covered as a 6.5-point underdog and the score was over the total of 40.5.

San Francisco (1-0 SU and ATS) beat the Seattle Seahawks 33-17 on Sept. 11 and cashed as a 6-point home favorite. The score went over the total of 38.

NFL Betting trends show a major over trend, as the total has gone over in all five of the past five meetings, in 13 of the Cowboys’ last 14 overall and in six of their last seven on the road, in five of San Francisco’s last six overall, and in four of San Francisco’s last five at home.

Head-to-head, the teams have split the past eight meetings straight up, each at 4-4, while the 49ers have a slight edge against the spread at 4-3-1 ATS. They last met on Nov. 23, 2008, when the Cowboys won 35-22 and covered as a 9.5-point home favorite.

The 2011 MLB All-Star Game takes place Tuesday at Chase Field in Phoenix, home of the Arizona Diamondbacks (8 pm ET, FOX).

MLB Odds have the National League as a -120 moneyline favorite and the over/under total at 8.5.

The game, often called the annual Midsummer Classic, pits the top players from each league against one another, but this season, the list of players who have pulled out for various reasons reads like a starting lineup for both sides.

American League players who will not be playing Tuesday include starters Derek Jeter, Alex Rodriguez and Mariano Rivera of the New York Yankees, Jon Lester of the Boston Red Sox, David Price of the Tampa Bay Rays, and Felix Hernandez of the Seattle Mariners.

National League starts not playing include Ryan Braun of the Milwaukee Brewers, Matt Cain of the San Francisco Giants, Cole Hamels of the Philadelphia Phillies, Chipper Jones of the Atlanta Braves, and Jose Reyes of the New York Mets.

With the Diamondbacks of the NL West division hosting this year’s event, the National League will be the home team.

NL starts include Prince Fielder, Placido Polanco, Jose Reyes, Brian McCann and Ryan Braun, Lance Berkman, with Roy Halladay of the Philadelphia Phillies the starting pitcher.

AL starters include Adrian Gonzalez, Robinson Cano, Jose Bautista, Curtis Granderson, Josh Hamilton and David Ortiz. The AL’s starting pitcher is Jerod Weaver of the Los Angeles Angels.

The National League won last year’s game 3-1, the first time the NL has won the All-Star Game since 1996.

Sports Picks previews the Los Angeles Angels and the Los Angeles Dodgers meeting Friday to open a three-game interleague set at Dodger Stadium (10:10 pm ET, FOX).

MLB Betting has the Angels as a -140 moneyline favorite and the over/under total at 6.5.

The Angels (37-39 SU) are 6-4 SU in their past 10 games and sit third in the AL West, three games behind the first-place Texas Rangers. The Dodgers (34-42 SU) are 4-6 SU in their past 10 and are fourth in the NL West, 7.5 games back of the first-place Arizona Diamondbacks.

The Angels will have righthander Dan Haren on the mound. Haren is 5-5 with a 2.99 ERA this season, and got his last start Sunday against the New York Mets, lasting just four innings in a 6-1 loss. The Dodgers will go with Rubby De La Rosa, who is 2-1 with a 5.52 ERA. The righthander’s last start was Sunday against the Houston Astros, when he went four and two-thirds innings in a 7-0 loss.

Also Friday, the Colorado Rockies and the New York Yankees open a three game interleague series at Yankee Stadium (7:05 pm ET, FOX).

MLB Odds have the Yankees as a -145 moneyline favorite and the over/under total at 9.

The Rockies (37-37 SU) are in third place in the NL West division, 3.5 games back of the first place Arizona Diamondbacks, while the Yankees (43-30 SU) are second in the AL East, but are just a half-game of the first-place Boston Red Sox.

Colorado will start righthander Ubaldo Jimenez, who is 2-7 with a 4.68 ERA. New York will start righthander AJ Burnett, who is 7-5 with a 4.05 ERA.

MLB Picks previews the final game of a three-game interleague set between the Los Angeles Angels and Florida Marlins on Wednesday at Sun Life Stadium (7:10 pm ET, FOX).

MLB Odds will have the Angels as favorites in this one, as the Marlins are immersed in the worst slump of the 2011 MLB season.

Florida has been brutal, losing 11 straight games and going 1-20 SU in their past 21. The Marlins are last in the NL East division, 13 games out of first place.

On Sunday, just before the Marlins lost their 10th straight to the Tampa Bay Rays, manager Edwin Rodriguez abruptly quit, and Florida announced former manager Jack McKeon, 80, would be the team’s interim manager. McKeon, who retired in 2005, becomes the second-oldest manager in MLB history.

Meanwhile, Los Angeles (36-38 SU) is 6-4 SU in its past 10 and sits third in the AL West division, three games back of the first place Texas Rangers.

The Angels will have righthander Joel Pineiro on the mound. He is 3-3 with a 3.92 ERA and last pitched Friday against the New York Mets, going six and one-third innings in a 4-3 win. The Marlins will give the ball to southpaw Brad Hand, who is 0-3 with a 3.45 ERA. He last started Friday against the Rays, lasting just four and two-thirds innings in a 5-1 loss.

The Angels won the opener 2-1 on Monday, cashing as a +112 road underdog. This is the first set of games between the teams since 2005, when LA won a three-game set 2-1.

Sports Picks sets up the Philadelphia Phillies and the St. Louis Cardinals opening a three-game set on Tuesday at Busch Stadium (8:15 pm ET, FOX).

MLB Odds have the Phillies as a -155 moneyline favorite for the opener, with the over/under total set at 7.5.

This matchup features a pair of National League division leaders, as the Phillies (45-28 SU) are in first place in the NL East, and the Cardinals (40-33 SU) are tied with the Milwaukee Brewers for first place in the NL Central.

But Philadelphia has been playing much better ball than St. Louis in recent games, with the Phillies going 8-2 SU in their past 10 and St. Louis going 3-7 SU.

Roy Halladay will get the start for the Phillies on Tuesday. The righthanded ace is 9-3 and has a 2.56 ERA, and his last start was Wednesday against the Florida Marlins, when he went seven innings in a 5-4 win. The Cardinals will have Kyle MCclellan on the mound. The righthander is 5-3 with a 4.05 ERA. He last pitched Wednesday against the Washington Nationals, lasting just five innings in a 10-0 blowout loss.

Head-to-head, the Cards are 6-4 SU in the past 10 meetings. Philadelphia and St. Louis have met once earlier this season, when the Cardinals swept a two-game series May 16-17. The under has hit in all four of the past four meetings, and in seven of the past 10.

The Phillies are coming off a 2-1 series loss against the Seattle Mariners, while the Cardinals beat the Kansas City Royals 2-1 in their three-game set.

Sports Picks previews the New York Yankees and the Chicago Cubs clashing in the second game of a three-game interleague series on Saturday at Wrigley Field (1:10 pm ET, FOX).

MLB Odds have the Yankees as a -135 moneyline favorite while the Cubs are a +155 underdog.

The pitchers in this matchup are righthander AJ Burnett for the Yankees and righthander Ryan Dempster for the Cubs.

So far this season, Burnett is 6-5 with a 4.09 ERA this season. His last start was Monday against the Cleveland Indians, when he went seven and two-thirds innings in a 1-0 loss. Dempster sports a 5-5 record with a 5.48 ERA, and he last pitched Monday when he went seven innings in a 1-0 win over the Milwaukee Brewers.

New York is 39-28 SU and sits second in the AL East. The Yankees entered play Friday 1.5 games back of the first-place Boston Red Sox, and are 6-4 SU in the past 10 games. Chicago is 28-40 SU this season and is fifth in the six-team NL Central division, 10 games behind the co-leading St. Louis Cardinals and the Milwaukee Brewers. The Cubs are 5-5 SU in their past 10.

Head-to-head, the teams have not met since 2005, when New York swept a three-game set at home. The Yankees are 4-2 SU in the past six meetings.

In their last action, the Yankees swept the Texas Rangers in a three-game series, winning the finale 3-2 as a +103 underdog on Thursday. Chicago is coming off a 3-1 series win against the Brewers.

MLB Picks sets up a key divisional battle when the Cleveland Indians and the Detroit Tigers finish off a three-game series Thursday at the Comerica Park (1:05 pm ET, FOX).

MLB Odds have the Tigers as a -165 moneyline favorite and the over/under total at 8.5.

The AL Central rivals are fighting for first place in the division, with Cleveland just one game back of first-place Detroit entering the second games of the series on Wednesday. But the teams have been headed in opposite directions in recent weeks, the Indians (35-30 SU) losing eight of their past 10 games and the Tigers (37-30 SU) winning seven of their last 10.

The Tigers took over sole possession of top spot in the AL Central with a 4-0 win in the opener of the series on Tuesday. Detroit cashed as a -175 home favorite and the score stayed under the total of 7.5.

Head-to-head, the Indians had dominated the eight meetings, going 6-2 SU, which included sweeping a three-game series April 29 to May 1 in the previous meeting between the teams this season. Cleveland won the last meeting of that series 5-4 as a -140 moneyline favorite.

Cleveland will have righthander Mitch Talbot on the mound. Talbot is 2-3 with a 4.01 ERA this season, and he last pitched Saturday when he went five and two-thirds innings in a 4-0 loss to the New York Yankees. Detroit will counter with righthander Max Scherzer, who is 8-2 with a 4.39 ERA. Scherzer’s last start also was Saturday, when he went seven innings in an 8-1 rout of the Seattle Mariners.

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