NFL Picks previews the Indianapolis Colts battling the Cincinnati Bengals in NFL Preseason action on Thursday at Paul Brown Stadium (7 pm ET, NFL Network).

NFL Odds have the Bengals as a 4-point favorite after opening at -6. The over/under total is at 36.

The Colts (10-6 SU, 8-8 ATS last season) won the AFC South division but didn’t last long in the NFL Playoffs, losing to the New York Jets in the Wild Card round. Cincinnati was 4-12 SU and 7-9 ATS, last in the AFC North.

The Colts are 7-3 SU and 5-5 ATS in the past 10 head-to-head meetings. Last year, the Colts beat the Bengals 23-17 on Nov. 14 but failed to cash as a 7-point home favorite.

Indianapolis is winless in the preseason, and last Friday lost to the Green Bay Packers after leading by eight points in the 4th quarter.

Cincinnati is 1-2 SU and ATS in preseason play. Last Thursday, the Bengals beat the Carolina Panthers 24-13, cashing as a 3-point home favorite.

Also Thursday, NFL Betting previews the Baltimore Ravens and the Atlanta Falcons meeting at the Georgia Dome.

NFL Betting Odds have Atlanta as a 3-point, -190 moneyline favorite and the over/under total at 38.

Baltimore (12-4 SU, 8-7-1 ATS last season) finished 2nd in the AFC North and 4th overall in the NFL, while Atlanta (13-3 SU, 11-5 ATS) was 1st in the NFC South.

Football Picks betting fans are buoyed by the news this week that Sports Illustrated has picked the Falcons to beat the San Diego Chargers in the 2012 Super Bowl.

Baltimore and Atlanta are both 2-2 SU and the Ravens 3-1 ATS in the past four head-to-head meetings.

NCAA Football Picks previews an opening day matchup between the Western Michigan Broncos and the Michigan Wolverines on Saturday at Michigan Stadium (3:30 pm ET, ABC).

NCAAF Odds had the Wolverines as a 14.5-point favorite but they’ve been bet down to -13.5.  On the moneyline, the Wolverines are a -540 favorite and Western Michigan is a +390 underdog. The over/under total opened at 59.5 and is now up to 61.

Western Michigan (6-6 SU, 4-5-2 ATS) was third in the Mid-American Conference West division standings last season. Michigan (7-6 SU, 3-9 ATS) was in seventh place in the Big Ten Conference. The Wolverines lost three straight down the stretch, including a 52-14 rout at the hands of the Mississippi State Bulldogs in the Gator Bowl.

The NCAA Betting experts who followed the Wolverines last season were provem wrong when they predicted Michigan would come out on top in the Big Ten, as the team rolled over when the conference championship and a high-profile bowl game were on the line.

Michigan was awful down the stretch, going 2-6 SU in its last eight and 0-5 ATS in its last five games overall, and 1-4 ATS in its last five games at home.

Western Michigan, on the other hand, was solid down the stretch, winning four of its last six games, including its last three straight. But the Broncos have not been good on the road, going 5-11 SU in their last 16 and 7-14-2 ATS in their last 23 away from home.

Everybody loves a winner!  Especially in the NFL, where parity is the standard.  Can you name the top 10 most profitable NFL teams from last year?  No?  Well you don’t have to…that’s why you have your own Dream Team working for you, Greatest Sports Picks.

Last year’s Gravy Train Cash Cow Award goes to … the Detroit Lions.  A 12-4 ATS record banked + 7.6 units for all the Motor City backers. The Lions covered 5 of 8 road contests and went 7-1  at home.  So far, they have covered all 3 pre-season games this year.

2. Atlanta Falcons, 11-5 ATS.  6-2 Road and 5-3 Home makes for a very solid campaign. + 5.5 Units

3. New England Patriots, 10-5-1 ATS.  6-2 Road warriors but so-so 4-3-1 at Gillette. +4.5 Units

4. Tampa Bay Buccaneers, 9-5-2 ATS. Top overall Road play, 7-0-1, but  a losing team at home, 2-5-1. +3.5 Units

5. St Louis Rams, 10-6 ATS. Home and Road winners 5-3…consistent. +3.4 Units

6. Pittsburgh Steelers, 10-6 ATS. Another consistent winning play, 5-3 Home and Road ATS. +3.4 Units

7. *Chicago Bears, 9-6-1 were a strong 5-2-1 ATS play on the road but average at home, 4-4 ATS. +2.8 Units (*Road only)

8. *Baltimore Ravens, 8-7-1 were another road play, 5-2-1 ATS but not a good home play, 3-5 ATS. +2.8 Units (*Road only)

9. *San Diego Chargers,8-7-1 ATS was strong at home, 6-2 but did not travel well, 2-5-1. +3.8 Units (*Home only)

10. *Miami Dolphins, 8-8 overall but an impressive 6-2 ATS Road play. +3.8 Units (*Road only)

Honorable Mention: Washington Redskins 8-5-3 Overall ATS, +2.5 Units;  Green Bay Packers, Jacksonville Jaguars, Kansas City Chiefs, and New York Jets were all 9-7 Overall ATS, + 1.3 Units.

College Football Picks previews an opening-day matchup when the No. 20 Mississippi State Bulldogs face the Memphis Tigers as NCAA Football kicks off another season on Thursday at the Liberty Bowl (8 pm ET, FSN).

NCAAF Odds opened with the Bulldogs as a 27.5-point favorite but they have now been bet up to 29-point faves. The over/under total has also climbed, from the opening odds of 48.5 up to 50.

Head-to-head, Mississippi State has absolutely dominated over the past nine meetings. The Bulldogs are a perfect 9-0 SU and 6-3 ATS. The Bulldogs and Tigers squared off last year, their first meeting since 2003. Mississippi State routed Memphis 49-7 and easily covered the spread as a 21.5-point home favorite. The score went over the total of 48.

Mississippi State (9-4 SU, 7-5 ATS last season) finished fifth in the always hotly contested SEC West division. The Bulldogs finished off the 2010 campaign with a 52-14 blowout win over the Michigan Wolverines in the Gator Bowl on Jan. 1.

The Tigers were awful last year, going 1-11 SU and 5-7 ATS. Memphis wound up last in the Conference USA East division.

NCAAF Betting trends show that after opening at 1-2 SU, the Bulldogs ended up winning eight of their final 10 games, and are 6-3 SU in their last nine games on the road. There is a strong under trend with five of Mississippi State’s last seven overall and four of its last five on the road staying under. Meanwhile, the Tigers are 0-5 SU and 1-4 ATS in their last five games at home.

NFL Football Picks previews the final preseason matchup between the Detroit Lions and the Buffalo Bills at Ralph Wilson Stadium on Thursday.

The Lions (6-10 SU, 12-4 ATS last season) finished last in the NFC North division, in a tie with the Minnesota Vikings, but have looked good in the exhibition season at 3-0 SU and ATS.

Detroit’s latest win may have been the best so far, as the Lions routed the New England Patriots 34-10 and covered as a 3-point home underdog. The score was under the total of 44.5.

Buffalo is 1-2 SU and ATS, and got its first win, a 35-32 victory over the Jacksonville Jaguars, on Saturday. The Bills could not cash as a 2.5-point home favorite and the score went over the total of 36.5.

But NFL Handicapping experts know that head-to-head, Buffalo is 3-1 SU and ATS in the past four meetings, and the teams met last season when the Bills edged the Lions 14-12 and covered as a 1.5-point home favorite.

Also Thursday, the Indianapolis Colts visit the Cincinnati Bengals at Paul Brown Stadium.

The Colts (10-6 SU, 8-8 ATS) won the AFC South division but are winless in the preseason. They lost 24-21 to the Super Bowl champion Green Bay Packers on Friday after leading 21-13 in the fourth quarter.

The Bengals (4-12 SU, 7-9 ATS) won their first preseason game Thursday, a 24-13 victory against the Carolina Panthers. They cashed as a 3-point home favorite.  

Head-to-head, the Colts are 7-3 SU and 5-5 ATS in the past 10 meetings in NFL Betting.

Free Football Picks sets up the New Orleans Saints and the Oakland Raiders squaring off in NFL preseason action on Sunday at the O.co Coliseum (8 pm ET, NBC).

NFL Odds opened with the Saints as a 4-point favorite, but they are now at -4.5 and -5 at many sportsbooks. New Orleans is a -200 to -220 moneyline fave and Oakland a +180 to +200 underdog. The over/under total has also been on the move, opening at 37 and now up to 38.5 at most books.

New Orleans (11-5 SU, 6-10 ATS last season) are at 1-1 straight up and against the spread in the preseason. The Saints beat the San Francisco 49ers 24-3 in their opener Aug. 12 and cashed as a 2.5-point home favorite. They then lost 27-14 against the Houston Texans as a 2.5-point road favorite Aug. 20.

Oakland (8-8 SU, 8-8 ATS) are 0-2 straight up and against the point spread. The Raiders lost their opener 24-18 against the Arizona Cardinals 24-18 on Aug. 11. And then last weekend, in a game that resulted in several skirmishes in the stands, the Raiders lost 17-3 to the San Francisco 49ers in the latest version of the Battle of the Bay.

NFL Betting trends show the Saints have dominated Oakland in recent head-to-head meetings, going 3-1 SU and ATS in the past four. They last squared off in 2008, when New Orleans romped to a 34-3 win and easily covered as 7-point home favorite.

New Orleans closes out the preseason with a home game against the Tennessee Titans Thursday, and Oakland hosts the Seattle Seahawks Friday.

NFL Picks previews a nationally televised preseason matchup between the New England Patriots and the Detroit Lions on Saturday at Ford Field (8 pm ET, CBS).

NFL Odds have the Patriots as a 4-point, -200 moneyline favorite and Detroit a +170 underdog. The over/under total opened at 44 and has moved up slightly to 44.5.

As many NFL Bettors know, the third week of the preseason is usually when teams will play their starters a lot, and while the Lions are expected to do just that, it looks like New England will give its prospects and other rookies a longer look.

Then again, the Patriots have little to prove, after coming off last season with the best regular-season record and going unbeaten in their two exhibition games.

NFL Betting fans were rewarded when New England opened with a 47-12 rout of the Jacksonville Jaguars, easily covering as a 3-point favorite. The score went over the total of 38. The Pats followed that with an equally dominating 31-14 win over the Tampa Bay Buccaneers last week, cashing as a 1-point road underdog. The score also went over the total of 33.

Detroit also is 2-0 SU and ATS in the preseason, blowing out the Cincinnati Bengals 34-3 in their opener as a 3-point home favorite, and then beating the Cleveland Browns 30-28 as a 2.5-point road underdog on Aug. 19.

Head-to-head, the Patriots have paid Football Betting fans straight up against the Lions at  3-1 SU in the past four meetings, but are 2-2 ATS. The teams met last season, when New England blew out the Lions 45-24 and cashed as 6.5-point road underdogs.

NFL Betting previews the defending Super Bowl champion Green Bay Packers taking on the Indianapolis Colts in NFL Preseason action Friday at Lucas Oil Stadium (8 pm, CBS).

NFL Picks have the Packers as an 8.5-point favorite after opening as a 9.5-point favorite. Green Bay is a -390 moneyline favorite and Indianapolis a +320 underdog. The over/under total is at 39 after opening at 38.5.

Both the Packers and Colts are 2-2 SU and ATS in the past four head-to-head meetings.

The Packers have split their first two preseason games, losing 27-17 to the Cleveland Browns on Aug. 13, failing to cover as a 2.5-point road underdog, and beating the Arizona Cardinals 28-20 as a 4.5-point home favorite last weekend.

The Colts have lost both preseason matchups, starting with a 33-10 loss against the St. Louis Rams in their opener on Aug. 13, and then losing 16-3 to the Washington Redskins on Aug. 19.

Also Friday, the St. Louis Rams battle the Kansas City Chiefs at Arrowhead Stadium.

NFL Odds started with the game as a pick’em, but St. Louis is now 1.5-point road favorite. The over/under total is at 35.    

The Rams opened the preseason with a 33-10 victory over the Indianapolis Colts, and then got past the Tennessee Titans 17-16 on Aug. 20. Kansas City has dropped both games, getting routed 25-0 by the Tampa Bay Buccaneers in their opener, and 31-13 by the Baltimore Ravens last Friday.  

Head-to-head, Kansas City is a perfect 5-0 SU and ATS in the past five meetings.

QUARTERBACK
Returning starter Geno Smith was able to practice and play this spring and that was great news considering he was questionable with another off-season foot surgery. Why was that important? Brand new offensive coordinator/quarterbacks coach Dana Holgorsen is implementing a completely new system. Getting reps and grasping this playbook is a necessary springboard for August. Mission accomplished as Smith finished 26-of-37 for 388 yards and four touchdowns in the spring game finale, albeit against the second team defense. Smith was able to make his cuts with both feet and showed no ill effects from his foot surgery. But Smith won’t be running with the ball in this offense. The days of quarterbacks being at the top of the rushing statistics are over. Last season Smith was criticized at times for his poor decisions and badly timed turnovers. But much of that blame was also directed at inept coaching, henceforth opening the door for the WVU administration to chase after Holgorsen. Look for Geno Smith to thrive in this system. He shows good form, a quick release and should excel in this offense throwing the ball. The back ups however are both true freshmen who enrolled early and that’s not a good sign at all should Smith go down at some point. Texas hurler Paul Millard came out on top this spring after leading the nation in passing as a high school senior. Also in the mix is Brian Athey from Minnesota, the grandson of WVU commentator Dwight Wallace. He is likely in line for a redshirt season barring injuries at this position.

West Virginia Mountaineers

RUNNING BACK
With Noel Devine moving on WVU will begin the season without a proven commodity at running back for the first time since 2005. Combine this with the fact the new offense is geared to air it out and the uncertainty of this 2011 rushing attack only gets bigger. That probably creates an uneasy feeling for Mountaineer fans knowing the last decade’s bread and butter has been one of the nation’s most prolific ground games. The identity of this offense is about to change in a major way and this is the one area that gets the majority of the facelift. New running back Coach Robert Gillespie divides his backfield between A backs (the lead ball carrier) and B backs (the blockers). Returning lead rusher Ryan Clarke has proven to be a force in short yardage and then some. The bullish 250-pounder looks like a nice fit for the blocking B-back spot and he will likely also see time at A-back where his rushing skills can be taken advantage of in different ways. Clarke sat out the spring after suffering torn cartilage in his knee during from the first scrimmage which allowed former walk-on Matt Lindamood to get most of the No. 1 reps. At the A-back spot Trey Johnson has carried the ball with authority thus far. He and true freshman Vernard Roberts, who enrolled early and led all rushers in the spring game, are smallish scat back types. Shawne Alston spelled Noel Devine last season when Devine was suffering with injury. He is the big back option between the tackles but also had his spring cut short with a sprained neck. The Morgantown chatter is that incoming freshman Andrew Buie will have a chance to be the featured ball carrier. Expect the carries to be split up. Getting anything close to a 1,000-yard back doesn’t seem likely under this scenario.

RECEIVER
One or maybe two of these receivers is going to be a star, count on it. And that is something else that will be a newly welcomed sight to Mountaineer fans. Who is the next Michael Crabtree or the next Justin Blackmon – two of the All-American, record setting receivers that have flourished under offensive coordinator Dana Holgorsen? That is how this offense works where an underrated high school prospect with gifted athletic skills can post colossal numbers in this “Air Raid”. The good news is that WVU has several of these types. The base sets will include four receivers, nothing new in Morgantown. What’s different is how they line up and get utilized. With two inside receivers and two outside receivers everybody gets a shot. At the top of the heap is all-time Maryland prep career rusher Tavon Austin. He is the team’s returning leading pass catcher but way too many times last year was ignored down the stretch. He can torment defenses across the middle using his shiftiness to turn short passes into big gainers. He has proven capable of stretching the field with his top end speed. If ever there was a player begging to be unshackled in a wide-open passing system, it is Tavon Austin. Another capable receiver that has proven to make clutch plays in tight spaces is Stedman Bailey. He has a chance to build on a stellar freshman campaign. Bailey lacks elite athleticism and size but has the ability to make the highlight catches. Along with Bradley Starks, Ivan McCartney is the tallest receiver in the rotation standing at 6’3. A ton of expectations have been placed on the shoulders of the Miramar, FL high school star. He possesses that elite NFL size and speed but he has yet to display anything that would leave coaches to believe he can contribute immediately. The former quarterback Starks was lost for the spring with a shoulder injury but if healthy is expected to finally make some noise his senior campaign. J.D. Woods turned out to be a nice surprise last season catching 18 passes. He can make a nice fifth or sixth option providing the needed depth although there may not be enough balls to go around. Pat White’s brother Coley, also a former quarterback, is now a full-time receiver in the mix. Ryan Nehlen, grandson of Hall of Fame WVU coach Don Nehlen, won the award this spring as the top walk-on and is good enough to see time on the field. There won’t be a tight end in these formations so Tyler Urban will be used as an inside receiver to create mismatches with smaller defensive backs. There really are quite a few options here, although Coach Holgorsen is still concerned with the lack of numbers. That’s how many receivers are required to work his magic.

OFFENSIVE LINE
This front wall is the biggest offensive question mark heading into the season once again. These same linemen crippled the offense on many occasions last year while failing to open holes for a once proud ground game. University of Arizona line coach and co-offensive coordinator Bill Bedenbaugh has been hired to resurrect this unit. His efforts were not made any easier when starting tackles Don Barclay and Jeff Braun sat out the spring with off-season shoulder surgery. The only silver lining was that young bull elephants Quentin Spain and Pat Eger got a chance to run with the first group while building the depth factor. It would not be surprising to see one of these mammoths wind up being the starter before 2011 comes to a close. Spain has a great upside after losing weight this winter while finding a dedication in the weight room. All-Big East senior Don Barclay has played in 39 career games, starting 27 and is the veteran of the group while Braun led the offensive line with 48 knockdowns and five thunderbolt blocks last year. Parkersburg product Josh Jenkins was once considered the number one high school player coming out of the state of West Virginia. He needs to rise up and perform like a college senior for this line to take an extensive step forward. Four starters are back and there is no reason for the continued sub par results. It might take a while for this group to get comfortable in the new system, which could slow down the early progress.

DEFENSIVE LINE
This defensive line did its job last year, that’s for sure. Those hefty numbers don’t lie. They helped lead a defense that ranked second nationally against the rush and second nationally at producing sacks. Two key clogs have departed in Scooter Berry and Chris Neild. The pass rush will still continue to rank with the best of them though, as defensive end Bruce Irvin should be the star of the defense. Irvin was a pass rushing specialist who emerged on the scene last fall as a first year JUCO transfer by recording 14 sacks while playing primarily on third downs. He has been working extremely hard to make the transition of being an every down player. After adding six pounds to his size while hitting the weight room, the senior is sure to garner double team attention from opposing teams. That leaves fellow senior Julian Miller on the other side to wreak havoc. Miller is actually the only returning starter on this line. He posted nine sacks in each of the past two seasons but has been moved from end to tackle in this 3-man defensive alignment. This will give Irvin more opportunities on the outside. Miller may weigh in a little light on the scale to play tackle but his quickness should be an advantage. Will Clarke showed promise at the beginning of last season before being slowed by a high ankle sprain. He will back up Irvin and with continued success can find time in certain packages. The battle to replace the wide-bodied (and NFL bound) bulldog Neild won’t be as simple. Jorge Wright and Josh Taylor have appeared in a combined 44 games. Wright made a move this spring to take over but his efforts got derailed after being suspended indefinitely for an arrest on May 3. Taylor has performed in more games and seen more starts. This line will be lighter in 2011, but it will also be quicker. It’s shaping up to continue being the best pass rush in the Big East. Continued achievement at stopping the run could be another story.

LINEBACKER
As with many positions on defense WVU will be looking for some new faces to step in at linebacker. No other unit will go through this much of a rebuilding effort with familiar names such as J.T. Thomas, Pat Lazear and Anthony Leonard graduating. The experience level is desperately slim. Holding down the fort will be fifth-year senior Najee Goode who luckily can play all three spots. The question is where does he fit best? Ironically, the official WVU spring depth chart has Goode starting at both the strong side and the weak side. While that scenario is comically impossible, it does demonstrate the need for someone else to step up. If Goode starts on the strong side that opens the door for Josh Francis, who just participated in his first spring here, on the weak side. Francis came from Lackawanna Jr. College in Scranton, PA where he was tabbed a First Team JUCO All-American. Francis emerging as a dependable starter would provide a huge boost. Currently operating with the first group on this side is senior walk-on Casey Vance. Another option is for two sophomores to start the opener in Branko Busick and Doug Rigg. The middle dons the least experience where Busick finished with three tackles on the season. His backup Jewone Snow redshirted. Between the two of them they registered fewer tackles than receiver J.D. Woods. At least Rigg saw some action last year and could be an option on the strong side. The New Jersey prepster played in all 13 games a year ago as a back up. Defensive Coordinator Jeff Casteel has proven he can produce more with less. This bunch has its shortcomings and Casteel will need to do his best work yet to make sure this group doesn’t spell disaster, especially early in the season.

DEFENSIVE BACK
Jeff Casteel will continue to implement the 3-3-5 stack defense, which equates to a need for quality defensive backs and plenty of them. Maintaining the numbers despite the loss of three key performers does not appear to be a problem with a young pipeline filling the gaps. Talent seems to be sufficient but experience does not. Rivals.com named Keith Tandy a Third Team All-American last December after leading the Big East with six interceptions. He will be the leader in this secondary. The departure of Brandon Hogan at the other cornerback spot won’t be easy to replace. Pat Miller is the front-runner after posting two starts a year ago. The speedy junior from Hoover High in Birmingham, AL was primarily used on third down situations so he knows what it takes to be in crucial situations. Washington DC product Avery Williams enrolled early as a true freshman this January and is making strides every day. He could wind up as part of this rotation. Spur safety Terence Garvin could be the best player in this secondary. After leading the team in tackles in 2011 as just a sophomore, Garvin is an imposing figure that has a great future. At free safety is Eain Smith who sat out the spring with injury. Smith has a reputation for being in the coaches’ doghouse, which means the door for talented youngster Travis Bell is wide open. Bell played in all 13 games as a true freshman. He is the tallest safety and can reportedly launch off the synthetic turf. The lack of experience is immediately felt at bandit safety where Darwin Cook was used solely as a back up last year. Pushing him is Wes Tonkery who redshirted. Overall, this unit cannot be expected to maintain the same type of production compared to a year ago. Nor will it meet the same potential as what could have been if Robert Sands had stayed in school. The cupboard is not bare by any means however and is far ahead of where this unit was just two seasons ago when Coach Lockwood took over.

Kicker Tyler Bitancurt returns after an extremely disappointing and inconsistent 2010 effort where he went 10-of-17 on field goal attempts. Bitancurt was selected as a First Team All-Big East selection in 2009 before his sophomore slump. He was just 2-of-7 from 40 yards and out. But his understanding of technique sets him apart from Corey Smith at present. This will be the fourth year in a row WVU needs to find a new punter. Big leg Corey Smith may not win the place kicker job but has the leading edge here. In 2007, the Musselman High Schooler was the best kicker/punter combination in the state. He enrolled at Alabama but found his way home transferring to Morgantown. Smith debuted as the kickoff man last year where eight of his boots resulted in touchbacks doubling the amount from the year prior. Broderick Jenkins is currently first in line to handle the punt returns. The turbo charged defensive back out of Fort Myers, FL has yet to catch a punt in a Blue and Gold uniform however. When it comes to returning kicks offs, just put Tavon Austin back deep and get out of the way. His average took a dip from the big year he had as a true frosh in ’09, which could be contributed to a shoulder injury he battled through. The early projection has Bradley Starks, one of the five fastest on the team, flanking Austin. This of course assumes Starks can recover from an injury bug that has plagued the senior. Coaches are looking for more production in the return department and hope to rectify the situation as they hired Daron Roberts away from the Detroit Lions to handle the special teams.

Free NFL Picks sets up the Washington Redskins and the Baltimore Ravens meeting in NFL preseason action Thursday at the M&T Bank Stadium (8 pm ET, ESPN).

NFL Odds have Baltimore as a 5-point favorite and a -230 moneyline favorite, while Washington is a +190 underdog. The over/under total is sitting at 33.5.

Head-to-head, the Ravens are 3-1 SU and ATS in the past four meetings, and all four games have been under the total.

The Redskins (6-10 SU, 10-5-1 ATS) are off to a great start in the preseason, with a 2-0 SU and ATS record in the preseason, beating the Indianapolis Colts 16-3 and covering as a 5-point road favorite in their last game.

The Ravens (12-4 SU, 8-7-1 ATS) are 1-1 SU and ATS, their last game a 31-13 win over the  Kansas City Chiefs on Aug. 19, cashing as a 7-point home favorite.

Also Thursday, the Cleveland Browns and the Philadelphia Eagles clash at Lincoln Financial Field.

NFL Betting has Philadelphia as a 7-point, -300 moneyline favorite and Cleveland a +250 moneyline underdog, with the over/under total at 39.5.

Head-to-head series, the Eagles are 3-0 SU in the past three meetings, but Cleveland has covered the spread at 2-1 ATS in those three matchups. They last clashed Dec. 15, 2008, a 30-10 Philadelphia win as a 16-point home favorite.

Cleveland (5-11 SU and ATS) lost 30-28 to the Detroit Lions on Friday, unable to cover as 2.5-point home favorites. Philadelphia (10-6 SU, 8-8 ATS) lost 24-14 to the Pittsburgh Steelers on Aug. 18, as a 2.5-point road underdog.

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